Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug

نویسندگان

  • Srinivas Garaga
  • Ambati V. Raghava Reddy
  • Koilpillai Joseph Prabahar
  • Raghu Babu Korupolu
  • Paul Douglas Sanasi
چکیده

Gatifloxacin is an antibacterial agent belonging to the fourth-generation fluoroquinolone family. Four piperazine-linked fluoroquinolone dimers of Gatifloxacin were observed during the laboratory process for Gatifloxacin and they were identified. The present work describes the origin, synthesis, characterization, and control of these dimers along with the synthesis of Despropylene Gatifloxacin (metabolite).

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عنوان ژورنال:

دوره 81  شماره 

صفحات  -

تاریخ انتشار 2013